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Phospho-eIF2 beta(Ser67) Polyclonal Antibody detects endogenous levels of eIF2 beta only when phosphorylated at Ser67.
Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: eIF2-beta; EIF2BA; Eukaryotic translation initiation factor 2 subunit 2; Eukaryotic translation initiation factor 2 subunit beta; eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa; protein phosphatase 1, regulatory subunit 67
基因别名: eIF-2-beta; EIF2; EIF2B; EIF2beta; EIF2S2; PPP1R67
UniProt ID: (Human) P20042
Entrez Gene ID: (Human) 8894