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Antibody detects endogenous levels of eIF2B epsilon only when phosphorylated at Ser540.
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B, a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: eIF-2B GDP-GTP exchange factor subunit epsilon; eIF2B GDP-GTP exchange factor subunit epsilon; eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa; initiation factor eIF-2Be; translation initiation factor eIF-2B subunit epsilon; Translation initiation factor eIF2B subunit epsilon
基因别名: C81315; CACH; CLE; EIF-2B; EIF2B5; EIF2BE; EIF2Bepsilon; LVWM
UniProt ID: (Human) Q13144, (Mouse) Q8CHW4, (Rat) Q64350
Entrez Gene ID: (Human) 8893, (Mouse) 224045, (Rat) 192234