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PlGF-1 Antibody (500-P226-1MG) in WB
Western Blot: To detect Human PlGF-1 by Western Blot analysis PlGF-1 Polyclonal Antibody (Product # 500-P226-1MG) can be used at a concentration of 0.1-0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human PlGF-1 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
产品信息
500-P226-1MG
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived Recombinant Human PlGF-1
偶联物
形式
Lyophilized
浓度
0.1-1.0 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
-20°C
运输条件
Ambient
RRID
AB_2929907
产品详细信息
AA Sequence of recombinant protein: MLPAVPPQQW ALSAGNGSSE VEVVPFQEVW GRSYCRALER LVDVVSEYPS EVEHMFSPSC VSLLRCTGCC GDENLHCVPV ETANVTMQLL KIRSGDRPSY VELTFSQHVR CECRPLREKM KPERCGDAVP RR.
Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human PlGF-1. Anti-Human PlGF-1-specific antibody was purified by affinity chromatography employing an immobilized Human PlGF-1 matrix.
Sandwich ELISA: To detect Human PlGF-1 by sandwich ELISA (using 100 µL/well antibody solution) a concentration of 0.5-2.0 µg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human PlGF-1 (500-P226Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human PlGF-1.
Western Blot: To detect Human PlGF-1 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human PlGF-1 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
靶标信息
PlGF-1 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-1 is expressed in placental tissues, the colon, and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor, and stimulates endothelial cell proliferation and migration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Placenta Growth Factor; Placenta Growth Factor-1; placental growth factor, vascular endothelial growth factor-related protein; PlGF
基因别名: D12S1900; PGF; PGFL; PIGF; PLGF; PlGF-2; SHGC-10760
UniProt ID: (Human) P49763
Entrez Gene ID: (Human) 5228
branching involved in ureteric bud morphogenesis
response to hypoxia
positive regulation of endothelial cell proliferation
sprouting angiogenesis
signal transduction
cell-cell signaling
female pregnancy
positive regulation of cell proliferation
cell differentiation
organ regeneration
cellular response to hormone stimulus
response to drug
positive regulation of angiogenesis
vascular endothelial growth factor receptor signaling pathway
positive regulation of cell division
regulation of morphogenesis of a branching structure
