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产品信息
MA5-19629
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2D8
抗原
PLEK (AAH18549, 121 a.a. ~ 230 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2609613
产品详细信息
Peptide Sequence: PETIDLGALY LSMKDTEKGI KELNLEKDKK IFNHCFTGNC VIDWLVSNQS VRNRQEGLMI ASSLLNEGYL QPAGDMSKSA VDGTAENPFL DNPDAFYYFP DSGFFCEENS
靶标信息
Major protein kinase C substrate of platelets.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ27168; p47; Platelet 47 kDa protein; Pleckstrin
基因别名: P47; PLEK
UniProt ID: (Human) P08567
Entrez Gene ID: (Human) 5341
hematopoietic progenitor cell differentiation
platelet degranulation
vesicle docking involved in exocytosis
integrin-mediated signaling pathway
positive regulation of platelet activation
negative regulation of inositol phosphate biosynthetic process
positive regulation of inositol-polyphosphate 5-phosphatase activity
cell projection organization
positive regulation of actin filament depolymerization
phospholipase C-inhibiting G-protein coupled receptor signaling pathway
cortical actin cytoskeleton organization
ruffle organization
actin cytoskeleton reorganization
positive regulation of actin filament bundle assembly
positive regulation of integrin activation
negative regulation of G-protein coupled receptor protein signaling pathway
phosphatidylinositol metabolic process
negative regulation of calcium-mediated signaling
regulation of cell diameter
thrombin receptor signaling pathway
platelet aggregation
protein kinase C signaling
protein secretion by platelet
