Invitrogen

Plexin-A1 Polyclonal Antibody

Plexin-A1 Antibody in Immunocytochemistry (ICC/IF)

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Plexin-A1 Antibody (PA5-47612) in ICC/IF

Immunocytochemistry analysis of Plexin-A1 in immersion fixed immature human dendritic cells. Samples were incubated in Plexin-A1 polyclonal antibody (Product # PA5-47612) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to cell surfaces and cytopl... View More

Plexin-A1 Antibody in Immunohistochemistry (Frozen) (IHC (F))

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产品信息

PA5-47612

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1 µg/mL

免疫组化（冰冻） (IHC (F))

5-15 µg/mL

免疫细胞化学 (ICC/IF)

5-15 µg/mL

产品规格

种属反应

Human, Mouse

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Mouse myeloma cell line NS0-derived recombinant mouse Plexin A1 Ser28-Pro1242

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS with 5% trehalose

内含物

No Preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2608297

产品详细信息

In direct ELISAs, less than 1% cross-reactivity with recombinant mouse (rm) Plexin A2 and rmPlexin A3 is observed.

Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

靶标信息

Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. [UniProt]

仅用于科研。不用于诊断过程。未经明确授权不得转售。