Invitrogen

Plexin A2 Monoclonal Antibody (583603)

Plexin A2 Antibody in Immunocytochemistry (ICC/IF)

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Plexin A2 Antibody (MA5-24263) in ICC/IF

Immunocytochemistry analysis of Plexin A2 in immersion fixed HUVEC human umbilical vein endothelial cells. Samples were incubated in Plexin A2 monoclonal antibody (Product # MA5-24263) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Rat IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to cell surfac... View More

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产品信息

MA5-24263

应用

建议稀释比

已发表文章

免疫印迹 (WB)

2 µg/mL

免疫组化（冰冻） (IHC (F))

查看1篇已发表文章 1篇已发表文章

免疫细胞化学 (ICC/IF)

8-25 µg/mL

产品规格

种属反应

Human, Mouse

已发表种属

Mouse

宿主/亚型

Rat / IgG2b

分类

Monoclonal

类型

Antibody

克隆号

583603

抗原

CHO-derived recombinant mouse Plexin A2 Met35-Pro1237

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.5 mg/mL

纯化类型

Protein A/G

保存液

PBS with 5% trehalose

内含物

No Preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2610104

产品详细信息

In direct ELISAs, no cross-reactivity with recombinant human Plexin A4, B1, B2, D1, recombinant mouse Plexin A1, A3, B3, or C1 is observed.

Reconstitute at 0.5 mg/mL in sterile PBS.

靶标信息

Plexins are a family of large, transmembrane receptors for multiple classes of semaphorins in vertebrates. Plexins are widely expressed, and regions of their extracellular domain are homologus to both scatter factor receptors and semaphorin domains. Plexins may act as semaphorin receptors alone or in combination with neuropilins. Plexins are divided into four subfamilies designated plexin-A, -B, -C, and -D. Drosophila plexin-A is a receptor for class I semaphorins and controls motor and axon guidance. Plexin-A3 mediates cell-repelling cues. Plexins B and C are receptors for Sema 4 and Sema 7, respectively.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Astrocyte endfoot formation controls the termination of oligodendrocyte precursor cell perivascular migration during development.

Neuron

Su Y,Wang X,Yang Y,Chen L,Xia W,Hoi KK,Li H,Wang Q,Yu G,Chen X,Wang S,Wang Y,Xiao L,Verkhratsky A,Fancy SPJ,Yi C,Niu J

MA5-24263 was used in Immunocytochemistry, Western Blot, Immunohistochemistry to demonstrate a correlation between the developmental formation of astrocytic endfeet on vessels and the termination of OPC perivascular migration.