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Prostacyclin Receptor (PTGIR) (extracellular) Antibody (APR-068-200UL) in WB
Western blot analysis of human Jurkat T-cell leukemia cell (lanes 1 and 4), human THP-1 monocytic leukemia cell (lanes 2 and 5) and human MEG-01 megakaryoblastic leukemia cell (lanes 3 and 6) lysates: - 1-3. Anti-Prostacyclin Receptor (PTGIR) (extracellular) Antibody (#APR-068), (1:200).4-6. Anti-Prostacyclin Receptor (PTGIR) (extracellular) Antibody , preincubated with Prostacyclin Receptor/PTGIR (extracel... View More
产品信息
APR-068-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)TQAIAPDSREMGD, corresponding to amino acid residues 290-302 of rat PTGIR, 3rd extracellular loop
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: IP receptor; PGI receptor; PGI2 receptor; Prostacyclin receptor; prostaglandin I receptor (IP); Prostaglandin I2 receptor; Prostanoid IP receptor
基因别名: IP; PGI2; PRIPR; PTGIR
UniProt ID: (Human) P43119, (Mouse) P43252, (Rat) P43253
Entrez Gene ID: (Human) 5739, (Mouse) 19222, (Rat) 292661
inflammatory response
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
cell-cell signaling
negative regulation of platelet-derived growth factor receptor signaling pathway
positive regulation of cAMP biosynthetic process
response to lipopolysaccharide
positive regulation of GTPase activity
positive regulation of cAMP-mediated signaling
negative regulation of smooth muscle cell proliferation
cellular response to prostaglandin D stimulus
signal transduction
G-protein coupled receptor signaling pathway
