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Immunogen sequence: VGIMVVSCIC WSPMLVLVAL AVGGWSSTSL QRPLFLAVRL ASWNQILDPW VYILLRQAVL RQLLRLLPPR AGAKGGPAGL GLTPSAWEAS SLRSSRHSGL S; Positive Samples: Mouse pancreas; Cellular Location: Cell membrane, Multi-pass membrane protein
The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: PGE receptor EP1 subtype; PGE2 receptor EP1 subtype; Prostaglandin E2 receptor EP1 subtype; Prostanoid EP1 receptor
基因别名: 42kDa; EP1; Ptger1; Ptgerep1
UniProt ID: (Mouse) P35375
Entrez Gene ID: (Mouse) 19216