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产品信息
PA1-4230
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptides corresponding to residues I(36) T Y V P P L L L E V G V E E(50) and F(537) A T Q V V F D K S D L A K Y S A(553) of human Prostein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2191100
产品详细信息
PA1-4230 detects the Prostein protein in human samples.
PA1-4230 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~55 kDa protein representing Prostein in metastatic adenocarcinoma LNCaP.FGC cells.
PA1-4230 immunogen is a mixture of synthetic peptides corresponding to the N- and C-terminal residues I(36) T Y V P P L L L E V G V E E(50) and F(537) A T Q V V F D K S D L A K Y S A(553) of human Prostein.
靶标信息
Prostein is a novel prostate-specific protein expressed in normal and malignant prostate tissues. This protein appears to be a type IIIa plasma membrane protein with a cleavable signal peptide and 11 transmembrane-spanning regions. Prostein expression is androgen responsive since treatment of LNCaP cells with androgen up-regulates prostein message and protein expression levels. Thus, prostein is a prostate-specific marker whose detection and quantitation may be useful in diagnosing and monitoring prostate cancer.
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生物信息学
蛋白别名: prostate cancer associated protein 2; prostate cancer associated protein 6; prostate cancer associated protein 8; prostate cancer-associated gene 2; prostate cancer-associated gene 6; prostate cancer-associated gene 8; Prostate cancer-associated protein 6; Prostein; Solute carrier family 45 member 3; solute carrier family 45, member 3
基因别名: IPCA-2; IPCA-6; IPCA-8; IPCA6; PCANAP2; PCANAP6; PCANAP8; PRST; SLC45A3
UniProt ID: (Human) Q96JT2
Entrez Gene ID: (Human) 85414
