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Immunogen sequence: MAALDSLSLF TSLGLSEQKA RETLKNSALS AQLREAATQA QQTLGSTIDK ATGILLYGLA SRLRDTRRLS FLVSYIASKK IHTEPQLSAA LEYVRSHPLD PIDTVDFERE CGVGVIVTPE QIEEAVEAAI NRHRPQLLVE RYHFNMGLLM GEARAVLKWA DGKMIKNEVD MQVLHLLGPK LEADLEKKFK VAKARLEETD RRTAKDVVEN GETADQTLSL MEQLRGEALK FHKPGENYKT PGYVVTPHTM; Positive Samples: HL-60, 293T, HeLa, Mouse testis; Cellular Location: Cytoplasm
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GlnRS; Glutamine--tRNA ligase; glutamine-tRNA ligase; glutamine-tRNA synthetase; Glutaminyl-tRNA synthetase
基因别名: 1110018N24Rik; 1200016L19Rik; C80286; GLNRS; MSCCA; PRO2195; QARS; QARS1
UniProt ID: (Human) P47897, (Mouse) Q8BML9
Entrez Gene ID: (Human) 5859, (Mouse) 97541