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Immunogen sequence: DKPRLISGVS RPDEVLECIE RGVDLFESFF PYQVTERGCA LTFSFDYQPN PEETLLQQNG TQEEIKCMDQ IKKIETTGC
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 90%.
Interacts with QTRT1 to form an active queuine tRNA-ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Queuine tRNA-ribosyltransferase accessory subunit 2; queuine tRNA-ribosyltransferase domain containing 1; Queuine tRNA-ribosyltransferase domain-containing protein 1
Gene Aliases: QTRT2; QTRTD1
UniProt ID: (Human) Q9H974
Entrez Gene ID: (Human) 79691
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