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This target displays homology in the following species: Cow: 100%; Dog: 93%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Interacts with QTRT1 to form an active queuine tRNA-ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
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Protein Aliases: Queuine tRNA-ribosyltransferase accessory subunit 2; Queuine tRNA-ribosyltransferase domain-containing protein 1; queuine tRNA-ribosyltransferase subunit QTRTD1
Gene Aliases: 3110012M05Rik; 4930470H18Rik; AI648807; Qtrt2; Qtrtd1
UniProt ID: (Mouse) B8ZXI1
Entrez Gene ID: (Mouse) 106248
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