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RAB3GAP2 Antibody (PA5-101804) in IHC (P)
Immunohistochemistry analysis of RAB3GAP2 in human pancreatic cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with RAB3GAP2 polyclonal antibody (Product # PA5-101804) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-101804
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human RAB3GAP2(Accession Q9H2M9), corresponding to amino acid residues A268-A318.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2851236
产品详细信息
Antibody detects endogenous levels of total RAB3GAP2.
靶标信息
The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: RAB3 GTPase activating protein subunit 2 (non-catalytic); Rab3 GTPase-activating protein 150 kDa subunit; Rab3 GTPase-activating protein non-catalytic subunit; Rab3-GAP p150; Rab3-GAP regulatory subunit; RAB3-GAP150; RGAP-iso
基因别名: 1110059F07Rik; 2010002H18Rik; 5830469C09; AI851069; AW743433; KIAA0839; mKIAA0839; p150; RAB3-GAP150; RAB3GAP150; RAB3GAP2; RGD1311518; SPG69; WARBM2
UniProt ID: (Human) Q9H2M9, (Mouse) Q8BMG7, (Rat) Q5U1Z0
Entrez Gene ID: (Human) 25782, (Mouse) 98732, (Rat) 289350
intracellular protein transport
regulation of GTPase activity
positive regulation of GTPase activity
establishment of protein localization to endoplasmic reticulum membrane
positive regulation of protein lipidation
positive regulation of endoplasmic reticulum tubular network organization
positive regulation of autophagosome assembly
