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This antibody is predicted to react with human, mouse, Xenopus and non-human primate based on 100% sequence homology.
In Western blot, this antibody is specific for ~27 kDa Rab 3 protein.
Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D. These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters. Specifically, Rab 3s are thought to play a key role in presynaptic vesicle trafficking and priming.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C18A3.6; RAS-associated protein RAB3A; Ras-related protein Rab-3A; Ras-related small GTP binding protein 3A
基因别名: RAB3; RAB3A
UniProt ID: (Human) P20336, (Rat) P63012, (Mouse) P63011
Entrez Gene ID: (Human) 5864, (Rat) 25531, (Mouse) 19339