Invitrogen

RAB5 Polyclonal Antibody

RAB5 Antibody in Immunocytochemistry (ICC/IF)

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RAB5 Antibody (PA3-915) in ICC/IF

Immunofluorescent analysis of RAB5 using anti-RAB5 polyclonal antibody (Product # PA3-915) shows staining in NS-1 Cells.

RAB5 Antibody in Immunohistochemistry (IHC)

Product Image Gallery

产品信息

PA3-915

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:5,000

免疫组化 (IHC)

查看1篇已发表文章 1篇已发表文章

免疫细胞化学 (ICC/IF)

1:250

查看5篇已发表文章 5篇已发表文章

产品规格

种属反应

Human, Rat

已发表种属

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant human Rab5.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

Conc. Not Determined

保存液

whole serum

内含物

0.05% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2177668

产品详细信息

PA3-915 detects Rab5 from human and rat samples.

PA3-915 has been successfully used in Western blot and immunofluorescence procedures.

The PA3-915 immunogen is recombinant human Rab5.

靶标信息

RAB5 are among the small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension. Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan. Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Efficient Protein Transfection by Swarms of Chemically Powered Plasmonic Virus-Sized Nanorobots.

ACS nano

Ressnerova A,Novotny F,Michalkova H,Pumera M,Adam V,Heger Z

PA3-915 was used in Immunocytochemistry-immunoflourescence to show that protein transfection mediated by such nanorobots is an important step forward, challenging the field of nanomedicine and having potential in future translational medical research.

Tue Aug 24 00:00:00 UTC 2021

Passive Diffusion vs Active pH-Dependent Encapsulation of Tyrosine Kinase Inhibitors Vandetanib and Lenvatinib into Folate-Targeted Ferritin Delivery System.

International journal of nanomedicine

Skubalova Z,Rex S,Sukupova M,Zahalka M,Skladal P,Pribyl J,Michalkova H,Weerasekera A,Adam V,Heger Z

PA3-915 was used in Immunocytochemistry to show that since the passive loading does not require a reassembly step for which acids are needed, the presented investigation serves as a solid basis for future studies focused on encapsulation of small hydrophobic molecules.

Fri Jan 29 00:00:00 UTC 2021

Norepinephrine transporter-derived homing peptides enable rapid endocytosis of drug delivery nanovehicles into neuroblastoma cells.

Journal of nanobiotechnology

Haddad Y,Charousova M,Zivotska H,Splichal Z,Merlos Rodrigo MA,Michalkova H,Krizkova S,Tesarova B,Richtera L,Vitek P,Stokowa-Soltys K,Hynek D,Milosavljevic V,Rex S,Heger Z

PA3-915 was used in Immunocytochemistry-immunoflourescence to demonstrate the drug delivery efficiency of the homing peptide GASNGINAYLC for use as a potential nanotherapy for neuroblastoma.

Mon Jul 13 00:00:00 UTC 2020

Norepinephrine transporter-derived homing peptides enable rapid endocytosis of drug delivery nanovehicles into neuroblastoma cells.

Journal of nanobiotechnology

Haddad Y,Charousova M,Zivotska H,Splichal Z,Merlos Rodrigo MA,Michalkova H,Krizkova S,Tesarova B,Richtera L,Vitek P,Stokowa-Soltys K,Hynek D,Milosavljevic V,Rex S,Heger Z

PA3-915 was used in Immunocytochemistry-immunoflourescence to demonstrate the drug delivery efficiency of the homing peptide GASNGINAYLC for use as a potential nanotherapy for neuroblastoma.