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Immunogen sequence: MSTGGDFGNP LRKFKLVFLG EQSVGKTSLI TRFMYDSFDN TYQATIGIDF LSKTMYLEDR TIRLQLWDTA GQERFRSLIP SYIRDSAAAV VVYDITNVNS FQQTTKWIDD VRTERGSDVI IMLVGNKTDL ADKRQVSIEE GERKAKELNV MFIETSAKAG YNVKQLFRRV AAALPGMEST QDRSREDMID IKLEKPQEQP; Positive Samples: BT-474, OVCAR3, SW480, HT-29, 293T, SH-SY5Y, Mouse brain, Mouse lung, Mouse intestine; Cellular Location: Golgi apparatus, Golgi apparatus membrane, Lipid-anchor
Rab proteins are also an integral part of endocytic pathways. Rab 6A is a ubiquitously expressed member of the Rab family of proteins and localizes to the Golgi membrane where it regulates retrograde transport from the late endosomes via the Golgi to endoplasmic reticulum (ER) pathway. Three isoforms exist due to alternative splicing events, namely the ubiquitously expressed isoforms Rab 6A' and Rab 6A, and the brain-specific isoform Rab 6B.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Rab GTPase; Rab-6; RAB6, member RAS oncogene family; Ras-related protein Rab-6A
基因别名: 2610028L11Rik; AA419671; MNCb-1660; RAB6; RAB6A
UniProt ID: (Human) P20340, (Mouse) P35279
Entrez Gene ID: (Human) 5870, (Mouse) 19346