Search Thermo Fisher Scientific
This antibody detects endogenous protein at a molecular weight of 42 kDa.
Purity is >95% by SDS-PAGE.
The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab superfamilies exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. Rab 8B (Ras-related protein Rab-8B) is a 207 amino acid lipid anchor that localizes to the cytoplasmic side of the cell membrane and belongs to the Rab family and small GTPase superfamily. Rab 8B may be involved in neurotransmitter release and vesicular trafficking, and is encoded by a gene located on human chromosome Rab 8B and mouse chromosome 9 C.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ38125; GTPase Rab8b; RAB-8b protein; RAB44, member RAS oncogene family; Ras-related protein Rab-8B
基因别名: 5930437D16; D330025I23Rik; RAB8B
UniProt ID: (Human) Q9P293, (Rat) P70550, (Mouse) P61028
Entrez Gene ID: (Human) 51762, (Rat) 266688, (Mouse) 235442