Invitrogen

RAB8B Polyclonal Antibody

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RAB8B Antibody (PA5-45012) in WB

Western blot analysis of human, mouse cell lysate using an anti-RAB8B polyclonal antibody (Product # PA5-45012).; Secondary Antibody: goat anti-Rabbit LANE 1)Human Cervical Cancer Cell Lysate (15µg); LANE 2) Monkey Fibroblast Cell Lysate (15µg); LANE 3) Human Cervical Cancer Cell transfected with mouse Rab8B-GFP (15µg).

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产品信息

PA5-45012

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide directed towards the C-terminal of human RAB8B (aa 104-153).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2606233

产品详细信息

Peptide sequence: RNIEEHASSD VERMILGNKC DMNDKRQVSK ERGEKLAIDY GIKFLETSAK

Sequence homology: Cow: 100%; Dog: 100%; Goat: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%; Zebrafish: 100%

靶标信息

The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab superfamilies exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. Rab 8B (Ras-related protein Rab-8B) is a 207 amino acid lipid anchor that localizes to the cytoplasmic side of the cell membrane and belongs to the Rab family and small GTPase superfamily. Rab 8B may be involved in neurotransmitter release and vesicular trafficking, and is encoded by a gene located on human chromosome Rab 8B and mouse chromosome 9 C.

仅用于科研。不用于诊断过程。未经明确授权不得转售。