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产品信息
PA5-67354
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2664303
产品详细信息
Immunogen sequence: SSANVEEAFFT LARDIMTKLN RKMNDSNSAG AGGPVKITEN RSKKTSFFRC SLL
Highest antigen sequence identity to the following orthologs - mouse 94%, rat 94%.
靶标信息
The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab superfamilies exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. Rab 8B (Ras-related protein Rab-8B) is a 207 amino acid lipid anchor that localizes to the cytoplasmic side of the cell membrane and belongs to the Rab family and small GTPase superfamily. Rab 8B may be involved in neurotransmitter release and vesicular trafficking, and is encoded by a gene located on human chromosome Rab 8B and mouse chromosome 9 C.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: FLJ38125; RAB-8b protein; Ras-related protein Rab-8B
基因别名: RAB8B
UniProt ID: (Human) Q9P293
Entrez Gene ID: (Human) 51762
vesicle docking involved in exocytosis
small GTPase mediated signal transduction
protein secretion
antigen processing and presentation
positive regulation of cell projection organization
adherens junction organization
cilium assembly
protein import into peroxisome membrane
positive regulation of corticotropin secretion
