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Product Details
MA1-16541
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Yeast
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
2H11/6
Immunogen
His-tagged human Rad 51C, over-expressed in E. coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4
Contains
0.02% sodium azide
Storage conditions
4° C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2177265
Product Specific Information
Suggested positive control: Hela whole cell extract.
Target Information
ZFPM1 is a transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. ZFPM1 is an essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. ZFPM1 may be involved in regulation of some genes in gonads. ZFPM1 may also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DNA repair protein RAD51 homolog 3; MGC104277; R51H3; RAD51 homolog C; RAD51-like protein 2; yeast RAD51 homolog 3
Gene Aliases: BROVCA3; FANCO; R51H3; RAD51C; RAD51L2
UniProt ID: (Human) O43502, (Mouse) Q924H5
Entrez Gene ID: (Human) 5889, (Mouse) 114714
double-strand break repair via homologous recombination
DNA repair
DNA recombination
cellular response to DNA damage stimulus
female meiosis sister chromatid cohesion
reciprocal meiotic recombination
male meiosis I
spermatogenesis
positive regulation of G2/M transition of mitotic cell cycle
nucleic acid phosphodiester bond hydrolysis
telomere maintenance via recombination
DNA recombinase assembly
DNA synthesis involved in DNA repair
strand displacement
mitotic recombination
sister chromatid cohesion
blood coagulation
response to ionizing radiation
strand invasion
chromosome organization involved in meiotic cell cycle
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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