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产品信息
PA5-21275
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment contain a sequence corresponding to a region within amino acids 197 and 391 of Rad9
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol, 1% BSA
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11152972
产品详细信息
Recommended positive controls: A431, HeLa, C2C12, Rat2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
RAD9 is a component of the 9-1-1 cell cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesions upon damage by the RAD17-replication factor C clamp loader complex. RAD9 acts as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cell cycle checkpoint control protein RAD9A; DNA repair exonuclease rad9 homolog A; hRAD9; mRAD9; RAD9 homolog A; RAD9 homolog A (S. pombe); Rad9-like protein; rCG47324-like
基因别名: RAD9; RAD9A
UniProt ID: (Human) Q99638, (Mouse) Q9Z0F6
Entrez Gene ID: (Human) 5883, (Mouse) 19367, (Rat) 100361529
DNA replication checkpoint
DNA damage checkpoint
DNA replication
DNA repair
cellular response to DNA damage stimulus
intra-S DNA damage checkpoint
cellular response to ionizing radiation
nucleic acid phosphodiester bond hydrolysis
regulation of signal transduction by p53 class mediator
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
cell cycle checkpoint
response to radiation
