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产品信息
PA5-75637
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length Human RAIDD.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2719365
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CASP2 and RIPK1 domain-containing adaptor with death domain; Caspase and RIP adapter with death domain; caspase and RIP adaptor with death domain; death adaptor molecule RAIDD; death domain containing protein CRADD; Death domain-containing protein CRADD; MGC9163; RIP-associated ICH1/CED3-homologous protein with death domain; RIP-associated protein with a death domain
基因别名: CRADD; MRT34; RAIDD
UniProt ID: (Human) P78560, (Mouse) O88843
Entrez Gene ID: (Human) 8738, (Mouse) 12905
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
signal transduction
regulation of apoptotic process
positive regulation of apoptotic signaling pathway
extrinsic apoptotic signaling pathway via death domain receptors
cellular response to mechanical stimulus
