Invitrogen

RALBP1 Polyclonal Antibody

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RALBP1 Antibody (PA5-88123) in WB

Western blot analysis of RALBP1 in extracts of various cell lines. Samples were incubated with RALBP1 Polyclonal antibody (Product # PA5-88123) using a dilution of 1:500, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.

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产品信息

PA5-88123

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 396-655 of human RALBP1 (NP_0067791)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

8.73 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2804670

产品详细信息

Immunogen sequence: AGIKEEIRRQ EFLLNCLHRD LQGGIKDLSK EERLWEVQRI LTALKRKLRE AKRQECETKI AQEIASLSKE DVSKEEMNEN EEVINILLAQ ENEILTEQEE LLAMEQFLRR QIASEKEEIE RLRAEIAEIQ SRQQHGRSET EEYSSESESE SEDEEELQII LEDLQRQNEE LEIKNNHLNQ AIHEEREAII ELRVQLRLLQ MQRAKAEQQA QEDEEPEWRG GAVQPPRDGV LEPKAAKEQP KAGKEPAKPS PSRDRKETSI; Positive Samples: A-673, Mouse spleen, Mouse lung; Cellular Location: Membrane, Peripheral membrane protein

靶标信息

Can specifically activate hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDC2 to switch off endocytosis, One of its substrates would be EPN1/Epsin.

仅用于科研。不用于诊断过程。未经明确授权不得转售。