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产品信息
MA5-32251
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
SC06-49
抗原
Recombinant protein within Human RALBP1 aa 205-300
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2809537
产品详细信息
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
Can specifically activate hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDC2 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 76 kDa Ral-interacting protein; Cytocentrin; Dinitrophenyl S-glutathione ATPase; DNP-SG ATPase; Ral-interacting protein 1; RalA-binding protein 1; RalBP1; RIP
基因别名: RALBP1; RIP1; RLIP; RLIP1; RLIP76
UniProt ID: (Human) Q15311, (Rat) Q62796, (Mouse) Q62172
Entrez Gene ID: (Human) 10928, (Rat) 84014, (Mouse) 19765
transport
endocytosis
chemotaxis
signal transduction
small GTPase mediated signal transduction
regulation of GTPase activity
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction
transmembrane transport
mitotic spindle organization
mitotic nuclear division
metabolic process
negative regulation of smooth muscle cell proliferation
cell division
