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RAN Antibody (PA5-87541) in WB
Western blot analysis of RAN in extracts of various cell lines. Samples were incubated with RAN Polyclonal antibody (Product # PA5-87541) using a dilution of 1:500, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-87541
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-216 of human Ran (NP_0063161)
偶联物
形式
Liquid
浓度
1.26 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2804238
产品详细信息
Immunogen sequence: MAAQGEPQVQ FKLVLVGDGG TGKTTFVKRH LTGEFEKKYV ATLGVEVHPL VFHTNRGPIK FNVWDTAGQE KFGGLRDGYY IQAQCAIIMF DVTSRVTYKN VPNWHRDLVR VCENIPIVLC GNKVDIKDRK VKAKSIVFHR KKNLQYYDIS AKSNYNFEKP FLWLARKLIG DPNLEFVAMP ALAPPEVVMD PALAAQYEHD LEVAQTTALP DEDDDL; Positive Samples: NIH/3T3, COS-1, COS-7, Jurkat, 293T, Mouse testis, rat testis, C6, mouse kidney; Cellular Location: Cytoplasm, Melanosome, Nucleus, Nucleus envelope
靶标信息
Ran (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The Ran protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of Ran requires the presence of regulator of chromosome condensation 1 (RCC1).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ARA25; GTP-binding nuclear protein Ran; GTPase Ran; OTTHUMP00000166078; OTTHUMP00000166102; Ras-like protein TC4; Ras-related nuclear protein
基因别名: Ran; Rasl2-8
UniProt ID: (Rat) P62828, (Mouse) P62827
Entrez Gene ID: (Rat) 84509, (Mouse) 19384
ribosomal large subunit export from nucleus
ribosomal small subunit export from nucleus
microtubule cytoskeleton organization
protein import into nucleus
protein export from nucleus
nucleocytoplasmic transport
mitotic nuclear division
small GTPase mediated signal transduction
spermatid development
metabolic process
actin cytoskeleton organization
positive regulation of protein binding
cellular protein localization
cellular protein complex localization
cell division
ribosomal subunit export from nucleus
protein import into nucleus, translocation
transport
intracellular protein transport
cell cycle
signal transduction
protein transport
regulation of protein binding
protein localization to nucleolus
