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RANBP1 Antibody (MA5-50503) in ICC/IF
Immunocytochemical analysis of RANBP1 using RANBP1 Recombinant Monoclonal Antibody (Product # MA5-50503) in HeLa cells at a dilution of 1:500. Cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: RanBP1 stained by RanBP1 antibody (MA5-50503) diluted at 1:500. Blue: Fluoroshield with DAPI.
产品信息
MA5-50503
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
HL2358
抗原
Recombinant fragmemt of human RanBP1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_3093816
靶标信息
Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HpaII tiny fragments locus 9A; HpaII tiny fragments locus 9a protein; Htf9-a/RanBP1; Ran-binding protein 1; Ran-specific GTPase-activating protein; RANBP1; RANG; testis secretory sperm-binding protein Li 221n
基因别名: Htf9-a; HTF9A; RANBP1
UniProt ID: (Human) P43487, (Mouse) P34022
Entrez Gene ID: (Human) 5902, (Mouse) 19385, (Rat) 360739
G1/S transition of mitotic cell cycle
RNA export from nucleus
ubiquitin-dependent protein catabolic process
protein import into nucleus
spindle organization
signal transduction
viral process
positive regulation of GTPase activity
positive regulation of mitotic centrosome separation
cell-cell adhesion
positive regulation of neuron projection development
intracellular transport
cellular response to leptomycin B
