Invitrogen

RANBP2 Polyclonal Antibody

RANBP2 Antibody in Immunohistochemistry (IHC)

图: 1 / 4

RANBP2 Antibody (PA1-082) in IHC

Immunohistochemical staining of RanBP2 in bovine retina using Product # PA1-082.

Product Image Gallery

产品信息

PA1-082

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1 µg/mL

查看1篇已发表文章 1篇已发表文章

免疫组化 (IHC)

10 µg/mL

其他PubMed (MISC)

查看2篇已发表文章 2篇已发表文章

产品规格

种属反应

Bovine, Human

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide corresponding to residues M(1) R R S K A D V E R Y I A S V Q G S(18) of human RanBP2.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS with 1mg/mL BSA

内含物

0.05% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_325806

产品详细信息

PA1-082 detects Ran binding protein 2 (RanBP2) from human and bovine retina.

PA1-082 has been successfully used in Western blot and immunohistochemistry procedures. By Western blot, this antibody detects an ~360 kDa protein representing RanBP2 from bovine retinal extracts. Immunohistochemical staining of bovine retina with PA1-082 results in cytoplasmic staining of cells within the inner nuclear layer as well as the ganglion cells.

The PA1-082 immunogen is a synthetic peptide corresponding to residues M(1) R R S K A D V E R Y I A S V Q G S(18) of human RanBP2. This sequence is completely conserved between human and mouse. The PA1-082 immunizing peptide (Cat. # PEP-137) is available for use in neutralization and control experiments.

靶标信息

RanBP2 interacts with the small GTP-binding protein Ran and forms a large multiprotein complex involved in many biological processes such as mRNA processing, nuclear transport, cell cycle control and postmitotic nuclear reassembly. The protein is identified by western blotting as an apparent molecular mass of 360 kD. It is involved in nucleation of microtubule and control of cell growth by interacting with many protein factors.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Species-specific vulnerability of RanBP2 shaped the evolution of SIV as it transmitted in African apes.

PLoS pathogens

Meyerson NR,Warren CJ,Vieira DASA,Diaz-Griferro F,Sawyer SL

PA1-082 was used in Western Blotting to confirm RanBP2 driving virus evolution during cross-species transmissions of simian immunodeficiency viruses, particularly in the transmissions to and between great ape species.

Thu Mar 01 00:00:00 UTC 2018

Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.

The FEBS journal

Asally M,Yasuda Y,Oka M,Otsuka S,Yoshimura SH,Takeyasu K,Yoneda Y

PA1-082 was used in immunocytochemistry and western blot to investigate the role of Nup358 in dynamic remodeling during muscle cell differentiation.

Tue Feb 01 00:00:00 UTC 2011

Sumoylation delays the ATF7 transcription factor subcellular localization and inhibits its transcriptional activity.

Nucleic acids research

Hamard PJ,Boyer-Guittaut M,Camuzeaux B,Dujardin D,Hauss C,Oelgeschläger T,Vigneron M,Kedinger C,Chatton B

PA1-082 was used in immunohistochemistry and western blot to study the mechanism for ATF7 protein modification by SUMO-1

Mon Apr 30 00:00:00 UTC 2007

生物信息学

蛋白别名: 358 kDa nucleoporin; acute necrotizing encephalopathy 1 (autosomal dominant); E3 SUMO-protein ligase RanBP2; Nuclear pore complex protein Nup358; nucleoporin 358; Nucleoporin Nup358; P270; Ran-binding protein 2; RanBP2; RBP2; transformation-related protein 2

查看更多收起

基因别名: ADANE; ANE1; BOS_11608; IIAE3; NUP358; RANBP2; TRP1; TRP2

查看更多收起

UniProt ID: (Human) P49792

查看更多收起

Entrez Gene ID: (Bovine) 785768, (Human) 5903

查看更多收起

功能

peptidyl-prolyl cis-trans isomerase activity ligase activity RNA binding protein binding zinc ion binding Ran GTPase binding SUMO transferase activity

参与通路