Invitrogen

RAP Polyclonal Antibody

RAP Antibody in Immunocytochemistry (ICC/IF)

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RAP Antibody (PA5-82324) in ICC/IF

Immunofluorecent analysis of RAP in human cell line A-431 using RAP Polyclonal Antibody (Product # PA5-82324). Staining shows localization to endoplasmic reticulum.

RAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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RAP Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of RAP demonstrates antibody specificity. Immunohistochemical analysis of RAP using anti-RAP Polyclonal Antibody (Product #PA5-82324), shows significant staining of RAP in placenta and shows minimal or weak staining in skeletal muscle tissues. The relative expression levels of RAP within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-82324

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化（石蜡） (IHC (P))

1:500-1:1,000

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human LRPAP1. Recombinant protein control fragment (Product #RP-102336).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2789483

产品详细信息

Immunogen sequence: RMEKLNQLWE KAQRLHLPPV RLAELHADLK IQERDELAWK KLKLDGLDED GEKEARLIRN LNVILAKYGL DGKKDARQVT SNSLSGTQED GLDDPRLEKL WHKAKTSGKF SGEELDKLWR EFLHHKEK

靶标信息

Interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: 39 kDa receptor-associated protein; Alpha-2-macroglobulin receptor-associated protein; Alpha-2-macroglobulin receptor-associated protein precursor (Alpha-2-MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP) (Heparin binding protein-44) (HBP-44); Alpha-2-MRAP; Gp330-binding 45 kDa protein; HBP-44; Heparin-binding protein 44; low density lipoprotein receptor related protein, associated protein 1; low density lipoprotein receptor-related protein associated protein 1; Low density lipoprotein receptor-related protein-associated protein 1; low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1); RAP

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基因别名: A2MRAP; A2RAP; AA617339; AI790446; alpha-2-MRAP; AU042172; C77774; HBP44; LRPAP1; MRAP; MYP23; RAP

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UniProt ID: (Human) P30533, (Rat) Q99068, (Mouse) P55302

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Entrez Gene ID: (Human) 4043, (Rat) 116565, (Mouse) 16976

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功能

asialoglycoprotein receptor activity protein binding heparin binding lipase binding receptor antagonist activity low-density lipoprotein particle receptor binding unfolded protein binding very-low-density lipoprotein particle receptor binding chaperone

参与通路

protein folding receptor-mediated endocytosis negative regulation of very-low-density lipoprotein particle clearance vesicle-mediated transport negative regulation of protein binding extracellular negative regulation of signal transduction negative regulation of beta-amyloid clearance negative regulation of receptor activity