Search Thermo Fisher Scientific
Immunogen sequence: KYDPTIEDFY RKEIEVDSSP SVLEILDTAG TEQFASMRDL YIKNGQGFIL
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%
RAP2A is a small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: RAP2, member of RAS oncogene family (K-rev); Ras-related protein Rap-2a; RbBP-30; RP11-128N14.2
基因别名: K-REV; KREV; RAP2; RAP2A; RbBP-30
UniProt ID: (Human) P10114
Entrez Gene ID: (Human) 5911