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产品信息
PA5-30144
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein fragment corresponding to a region within amino acids 1 and 149 of Human RAP2B
偶联物
形式
Liquid
浓度
0.97 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2547618
产品详细信息
Recommended positive controls: A431, H1299, HepG2, mouse brain.
Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (98%), Xenopus laevis (96%), Pig (100%), Rhesus Monkey (100%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Ras-related protein Rap-2b; small GTP binding protein
基因别名: 4021402C18Rik; AA408554; RAP2B
UniProt ID: (Human) P61225, (Mouse) P61226
Entrez Gene ID: (Human) 5912, (Mouse) 74012
signal transduction
microvillus assembly
platelet activation
negative regulation of cell migration
positive regulation of protein autophosphorylation
Rap protein signal transduction
regulation of protein tyrosine kinase activity
platelet aggregation
establishment of endothelial intestinal barrier
small GTPase mediated signal transduction
