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RASGRF2 Antibody (PA5-115827) in IHC (P)
Immunohistochemistry analysis of RASGRF2 in mouse brain tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with RASGRF2 polyclonal antibody (Product # PA5-115827) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-115827
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human RASGRF2(Accession O14827), corresponding to amino acid residues F54-G104.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2900461
产品详细信息
Antibody detects endogenous levels of total RASGRF2.
靶标信息
RAS (MIM 190020) GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. Guanine-nucleotide exchange factors (GEFs), such as RASGRFs, stimulate the conversion of the GDP-bound form into the active form.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: guanine nucleotide-releasing factor 2; Ras guanine nucleotide exchange factor 2; Ras protein-specific guanine nucleotide-releasing factor 2; Ras-GRF2; Ras-specific guanine nucleotide-releasing factor 2
基因别名: 6330417G04Rik; AW048350; GRF2; RAS-GRF2; RASGRF2
UniProt ID: (Human) O14827, (Mouse) P70392, (Rat) Q99JE4
Entrez Gene ID: (Human) 5924, (Mouse) 19418, (Rat) 114513
MAPK cascade
small GTPase mediated signal transduction
regulation of Rho protein signal transduction
positive regulation of apoptotic process
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction
long-term synaptic potentiation
regulation of N-methyl-D-aspartate selective glutamate receptor activity
biological_process
