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产品信息
PA5-28857
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 403 and 621 of Human Ras GRF2
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2546333
产品详细信息
Recommended positive controls: mouse brain.
Predicted reactivity: Mouse (95%), Rat (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
RAS (MIM 190020) GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. Guanine-nucleotide exchange factors (GEFs), such as RASGRFs, stimulate the conversion of the GDP-bound form into the active form.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ras guanine nucleotide exchange factor 2; Ras protein-specific guanine nucleotide-releasing factor 2; Ras-GRF2; Ras-specific guanine nucleotide-releasing factor 2
基因别名: 6330417G04Rik; AW048350; GRF2; RAS-GRF2; RASGRF2
UniProt ID: (Human) O14827, (Mouse) P70392
Entrez Gene ID: (Human) 5924, (Mouse) 19418
MAPK cascade
small GTPase mediated signal transduction
regulation of Rho protein signal transduction
positive regulation of apoptotic process
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction
long-term synaptic potentiation
regulation of N-methyl-D-aspartate selective glutamate receptor activity
