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产品信息
H00010235-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
RASGRP2 (NP_005816.2, 1 a.a. approximately 671 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGTQRLCGRG TQGWPGSSEQ HVQEATSSAG LHSGVDELGV RSEPGGRLPE RSLGPAHPAP AAMAGTLDLD KGCTVEELLR GCIEAFDDSG KVRDPQLVRM FLMMHPWYIP SSQLAAKLLH IYQQSRKDNS NSLQVKTCHL VRYWISAFPA EFDLNPELAE QIKELKALLD QEGNRRHSSL IDIDSVPTYK WKRQVTQRNP VGQKKRKMSL LFDHLEPMEL AEHLTYLEYR SFCKILFQDY HSFVTHGCTV DNPVLERFIS LFNSVSQWVQ LMILSKPTAP QRALVITHFV HVAEKLLQLQ NFNTLMAVVG GLSHSSISRL KETHSHVSPE TIKLWEGLTE LVTATGNYGN YRRRLAACVG FRFPILGVHL KDLVALQLAL PDWLDPARTR LNGAKMKQLF SILEELAMVT SLRPPVQANP DLLSLLTVSL DQYQTEDELY QLSLQREPRS KSSPTSPTSC TPPPRPPVLE EWTSAAKPKL DQALVVEHIE KMVESVFRNF DVDGDGHISQ EEFQIIRGNF PYLSAFGDLD QNQDGCISRE EMVSYFLRSS SVLGGRMGFV HNFQESNSLR PVACRHCKAL ILGIYKQGLK CRACGVNCHK QCKDRLSVEC RRRAQSVSLE GSAPSPSPMH SHHHRAFSFS LPRPGRRGSR PPEIREEEVQ TVEDGVFDIH L
靶标信息
The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Calcium and DAG-regulated guanine nucleotide exchange factor I; calcium and diacylglycerol-regulated guanine nucleotide exchange factor I; CalDAG-GEFI; Cdc25-like protein; F25B3.3 kinase-like protein; guanine exchange factor MCG7; hCDC25L; RAS guanyl nucleotide-releasing protein 2; RAS guanyl releasing protein 2 (calcium and DAG-regulated); RAS guanyl-releasing protein 2
基因别名: CALDAG-GEFI; CDC25L; MCG7; RASGRP2
UniProt ID: (Human) Q7LDG7
Entrez Gene ID: (Human) 10235
