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Positive test controls include: MCF7, NCI-H460, HeLa, Mouse spleen, Mouse brain, Mouse thymus, Rat liver. The target is usually found in the following locations: Nucleus.
Immunogen sequence: SIWAQNQVEN WSAFAPDFKE LDENVEYEER ESEFDIEDED KSEPEQTGAD AAEDEEVDVT SVDPIAAFCS SDEELEDSKA LLYLPIAPEV EDPEENPYGP PPDAVQTSLM DEGASSEKKR QSSADGSQPP KKKPKTTNIE LQGVPNDEVH PLLGVKGDGK SKKKQAGRPK GSKGKEKDSP FKPKLYKGDR GLPLEGSAKG KVQAELSQPL TAGGAISELL
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: RBBP 5; RBBP-5; RBQ 3; retinoblastoma binding protein 5; Retinoblastoma-binding protein 5; Retinoblastoma-binding protein RBQ-3; SWD1, Set1c WD40 repeat protein, homolog
基因别名: 4933411J24Rik; C330016J05; RBBP5; RBQ3; SWD1
UniProt ID: (Human) Q15291, (Mouse) Q8BX09
Entrez Gene ID: (Human) 5929, (Rat) 304794, (Mouse) 213464