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产品信息
PA5-89036
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 110-220 of human RBM14 (NP_0063191)
偶联物
形式
Liquid
浓度
3.33 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805311
产品详细信息
Immunogen sequence: VVKDYAFVHM EKEADAKAAI AQLNGKEVKG KRINVELSTK GQKKGPGLAV QSGDKTKKPG AGDTAFPGTG GFSATFDYQQ AFGNSTGGFD GQARQPTPPF FGRDRSPLRR S
Positive Samples: Mouse thymus, Mouse brain, Mouse eye, Rat brain; Cellular Location: Nucleus, nucleolus
靶标信息
Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: coactivator activator; Paraspeckle protein 2; PSP2; rna-binding; RNA-binding motif protein 14; RNA-binding protein 14; RRM-containing coactivator activator/modulator; synaptotagmin interacting protein; Synaptotagmin-interacting protein; SYT-interacting protein; transmembrane protein 137
基因别名: 1300007E16Rik; COAA; p16; p16K; PSP2; RBM14; SIP; Sytip; SYTIP1; TMEM137
UniProt ID: (Human) Q96PK6, (Mouse) Q8C2Q3
Entrez Gene ID: (Human) 10432, (Rat) 170900, (Mouse) 56275
DNA replication
DNA repair
DNA recombination
transcription, DNA-templated
response to hormone
histone deacetylation
intracellular estrogen receptor signaling pathway
glucocorticoid receptor signaling pathway
positive regulation of transcription from RNA polymerase II promoter
negative regulation of centriole replication
SMAD protein signal transduction
centriole assembly
regulation of transcription, DNA-templated
