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产品信息
A300-864A
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 1 and 50 of human RNA Binding Motif Protein 9.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
tris citrate/phosphate, pH 7-8
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
靶标信息
This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.
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生物信息学
蛋白别名: Fox-1 homolog B; Fox-1 homolog Fxh; fox-1 homologue; Fyn-binding molecule 2; Hexaribonucleotide-binding protein 2; Repressor of tamoxifen transcriptional activity; RNA binding motif protein 9; RNA binding protein fox-1 homolog 2; RNA binding protein, fox-1 homolog (C. elegans) 2; RNA-binding motif protein 9; RNA-binding protein 9
基因别名: dJ106I20.3; Fbm2; Fox-2; FOX2; Fxh; HNRBP2; HRNBP2; RBFOX2; RBM9; RTA
UniProt ID: (Human) O43251, (Rat) A1A5R1, (Mouse) Q8BP71
Entrez Gene ID: (Human) 23543, (Rat) 362950, (Mouse) 93686
regulation of alternative mRNA splicing, via spliceosome
mRNA processing
nervous system development
RNA splicing
fibroblast growth factor receptor signaling pathway
regulation of definitive erythrocyte differentiation
RNA metabolic process
radial glia guided migration of Purkinje cell
intracellular estrogen receptor signaling pathway
regulation of cell proliferation
negative regulation of transcription, DNA-templated
dendrite morphogenesis
neuromuscular process controlling balance
regulation of RNA splicing
