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RBP4 Antibody (MA5-29764) in ICC/IF
Immunofluorescence staining of mouse RBP4 in mouse splenocytes. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with RBP4 Recombinant Rabbit Monoclonal Antibody (8) (Product # MA5-29764, 1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green).
产品信息
MA5-29764
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
008
抗原
Recombinant Mouse RBP4 protein (Met1-Leu201)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2785587
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Mouse RBP4.
靶标信息
This protein belongs to the lipocalin family and is the specific carrier for retinol in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post translationally and results in defective delivery and supply to the epidermal cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Plasma retinol binding protein 4 (PRBP); Plasma retinol-binding protein; PRBP; RBP; retinol; retinol binding; Retinol binding protein 4 interstitial; retinol binding protein 4, cellular; Retinol-binding protein 4
基因别名: Rbp-4; Rbp4
UniProt ID: (Mouse) Q00724
Entrez Gene ID: (Mouse) 19662
eye development
gluconeogenesis
transport
spermatogenesis
heart development
male gonad development
embryo development
maintenance of gastrointestinal epithelium
lung development
positive regulation of insulin secretion
response to retinoic acid
response to insulin
retinol transport
retinol metabolic process
retinal metabolic process
glucose homeostasis
embryonic organ morphogenesis
embryonic skeletal system development
cardiac muscle tissue development
female genitalia morphogenesis
detection of light stimulus involved in visual perception
positive regulation of immunoglobulin secretion
vitamin transport
retina development in camera-type eye
negative regulation of cardiac muscle cell proliferation
embryonic retina morphogenesis in camera-type eye
uterus development
vagina development
urinary bladder development
heart trabecula formation
