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RCC1 Antibody (MA5-37820) in IHC (P)
Immunohistochemistry analysis of RCC1 in paraffin-embedded human placenta. Samples were incubated with RCC1 Monoclonal antibody (Product # MA5-37820) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Product Details
MA5-37820
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
ARC1834
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RCC1 (P18754)
Conjugate
Form
Liquid
Concentration
0.51 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2897743
Product Specific Information
Positive Samples: HeLa, Raji, SH-SY5Y, Mouse spleen, Mouse thymus, Rat testis
Immunogen sequence: MSPKRIAKRR SPPADAIPKS KKVKVSHRSH STEPGLVLTL GQGDVGQLGL GENVMERKKP ALVSIPEDVV QAEAGGMHTV CLSKSGQVYS FGCNDEGALG
Target Information
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell cycle regulatory protein; Chromosome condensation protein 1; guanine nucleotide-releasing protein; Regulator of chromosome condensation; SNHG3-RCC1 readthrough
Gene Aliases: 4931417M11Rik; AI326872; CHC1; RCC1; RCC1-I; SNHG3-RCC1
UniProt ID: (Human) P18754, (Mouse) Q8VE37
Entrez Gene ID: (Human) 1104, (Mouse) 100088, (Rat) 682908
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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