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产品信息
PA5-27100
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 400 and 649 of Human RecQ1
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2544576
产品详细信息
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, NIH-3T3.
Predicted reactivity: Pig (82%), Bovine (82%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5' and 3' UTRs, have been described.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATP-dependent DNA helicase Q1; DNA 3'-5' helicase Q1; DNA helicase, RecQ-like type 1; DNA-dependent ATPase Q1; RecQ helicase-like; RecQ protein-like (DNA helicase Q1-like); RecQ protein-like 1; RecQ1
基因别名: RECQ1; RECQL; RECQL1
UniProt ID: (Human) P46063, (Mouse) Q9Z129
Entrez Gene ID: (Human) 5965, (Mouse) 19691
DNA binding
DNA helicase activity
ATP-dependent DNA helicase activity
protein binding
ATP binding
four-way junction helicase activity
annealing helicase activity
ATP-dependent 3'-5' DNA helicase activity
nucleotide binding
nucleic acid binding
helicase activity
ATP-dependent helicase activity
hydrolase activity
DNA helicase
