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产品信息
PA5-51377
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2646489
产品详细信息
Immunogen sequence: LSRLDTLETS KRKSLQLLTK DSDKVKEFFE KLQHTLDQKK NEILSDFETM KLAVMQAYDP EINKLNTILQ EQRMAFNIAE AFKDVSEPIV FLQQMQEFRE KIKVIKETPL PPSNLPASPL MKNFDTSQWE DIKLVDVDKL SLP
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 97%.
靶标信息
The protein encoded by the RFP2 gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies near the nucleus, but its function is unknown. The gene is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia.
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生物信息学
蛋白别名: B-cell chronic lymphocytic leukemia tumor suppressor Leu5; CLL-associated RING finger; E3 ubiquitin-protein ligase TRIM13; Leukemia-associated protein 5; Putative tumor suppressor RFP2; Ret finger protein 2; RING finger protein 77; RING-type E3 ubiquitin transferase TRIM13; tripartite motif protein 13; tripartite motif-containing 13; Tripartite motif-containing protein 13
基因别名: CAR; DLEU5; LEU5; RFP2; RNF77; TRIM13
UniProt ID: (Human) O60858
Entrez Gene ID: (Human) 10206
signal transduction
anatomical structure morphogenesis
response to gamma radiation
positive regulation of cell death
positive regulation of macroautophagy
ER-associated ubiquitin-dependent protein catabolic process
negative regulation of viral transcription
positive regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
innate immune response
positive regulation of NF-kappaB transcription factor activity
protein autoubiquitination
negative regulation of viral release from host cell
