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产品信息
H00005992-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
RFX4 (NP_115880.2, 1 a.a. approximately 641 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MNWAAFGGSE FFIPEGIQID SRCPLSRNIT EWYHYYGIAV KESSQYYDVM YSKKGAAWVS ETGKKEVSKQ TVAYSPRSKL GTLLPEFPNV KDLNLPASLP EEKVSTFIMM YRTHCQRILD TVIRANFDEV QSFLLHFWQG MPPHMLPVLG SSTVVNIVGV CDSILYKAIS GVLMPTVLQA LPDSLTQVIR KFAKQLDEWL KVALHDLPEN LRNIKFELSR RFSQILRRQT SLNHLCQASR TVIHSADITF QMLEDWRNVD LNSITKQTLY TMEDSRDEHR KLITQLYQEF DHLLEEQSPI ESYIEWLDTM VDRCVVKVAA KRQGSLKKVA QQFLLMWSCF GTRVIRDMTL HSAPSFGSFH LIHLMFDDYV LYLLESLHCQ ERANELMRAM KGEGSTAEVR EEIILTEAAA PTPSPVPSFS PAKSATSVEV PPPSSPVSNP SPEYTGLSTT GAMQSYTWSL TYTVTTAAGS PAENSQQLPC MRNTHVPSSS VTHRIPVYPH REEHGYTGSY NYGSYGNQHP HPMQSQYPAL PHDTAISGPL HYAPYHRSSA QYPFNSPTSR MEPCLMSSTP RLHPTPVTPR WPEVPSANTC YTSPSVHSAR YGNSSDMYTP LTTRRNSEYE HMQHFPGFAY INGEASTGWA K
靶标信息
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. This protein may be a transcriptional repressor rather than a transcriptional activator. Three transcript variants encoding different isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Regulatory factor X 4; regulatory factor X, 4 (influences HLA class II expression); Testis development protein NYD-SP10; Transcription factor RFX4; winged-helix transcription factor RFX4
基因别名: NYD-SP10; RFX4
UniProt ID: (Human) Q33E94
Entrez Gene ID: (Human) 5992
transcription from RNA polymerase II promoter
dorsal spinal cord development
telencephalon development
cerebellar cortex morphogenesis
negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
midbrain development
cilium assembly
positive regulation of transcription from RNA polymerase II promoter
regulation of protein processing
