Invitrogen

RFX4 Polyclonal Antibody

RFX4 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 7

RFX4 Antibody (PA5-62205) in ICC/IF

Immunofluorescent staining of RFX4 in human cell line AF22 using a RFX4 Polyclonal Antibody (Product # PA5-62205) shows localization to nucleus.

RFX4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

RFX4 Antibody in Immunohistochemistry (IHC)

Product Image Gallery

RFX4 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of RFX4 demonstrates antibody specificity. Immunohistochemical analysis of RFX4 using anti-RFX4 Polyclonal Antibody (Product # PA5-62205), shows significant staining of RFX4 in human testis and shows minimal or weak staining in human endometrium tissues. The relative expression levels of RFX4 within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-62205

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human RFX4. Recombinant protein control fragment (Product #RP-101198).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2646495

产品详细信息

Immunogen sequence: STTGAMQSYT WSLTYTVTTA AGSPAENSQQ LPCMRNTHVP SSSVTHRIPV YPHREEHGYT GSYNYGSYGN QHPHPMQSQY PALPH

Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 95%.

靶标信息

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. This protein may be a transcriptional repressor rather than a transcriptional activator. Three transcript variants encoding different isoforms have been described for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: Regulatory factor X 4; regulatory factor X, 4 (influences HLA class II expression); Testis development protein NYD-SP10; Transcription factor RFX4; winged-helix transcription factor RFX4

查看更多收起

基因别名: NYD-SP10; RFX4

查看更多收起

UniProt ID: (Human) Q33E94

查看更多收起

Entrez Gene ID: (Human) 5992

查看更多收起

功能

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding protein binding winged helix/forkhead transcription factor

参与通路

transcription from RNA polymerase II promoter dorsal spinal cord development telencephalon development cerebellar cortex morphogenesis negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning midbrain development cilium assembly positive regulation of transcription from RNA polymerase II promoter regulation of protein processing