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RGPD5 Antibody (PA5-104056) in IHC (P)
Immunohistochemistry analysis of RGPD5 in mouse testis tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with RGPD5 polyclonal antibody (Product # PA5-104056) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-104056
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human RGPD5; RGPD6(Accession Q99666), corresponding to amino acid residues N204-E254.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2853385
产品详细信息
Antibody detects endogenous levels of total RGPD5.
靶标信息
The RANBP2-like and GRIP domain containing 5 protein (RGPD5) has high similarity to RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex. The gene coding for RGPD5 is thought to have arisen from a gene duplication event of RANBP2 as these highly homologous genes are located close to each other at chromosome 2q11-q12. RGPD5 was identified as an HIV dependency factor (HDF), suggesting that RGPD5 may be an important drug target in HIV treatment. At least two isoforms of RGPD5 are known to exist, of which the shorter isoform is expressed primarily in testis, while the longer of the two is expressed at low levels in a number of somatic tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: epididymis luminal protein 161; ran-binding protein 2-like 1; Ran-binding protein 2-like 1/2; ranBP2-like 1; RanBP2-like 1/2; RANBP2-like and GRIP domain-containing protein 5; RANBP2-like and GRIP domain-containing protein 5/6; ranBP2L1; RANBPL1; Sperm membrane protein BS-63
基因别名: BS-63; BS63; HEL161; RANBP2L1; RANBP2L2; RGP5; RGP6; RGP7; RGPD5; RGPD6; RGPD7
UniProt ID: (Human) Q99666
Entrez Gene ID: (Human) 84220
