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RGS20 Antibody (PA5-104093) in ICC/IF
Immunocytochemistry analysis of RGS20 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with RGS20 polyclonal antibody (Product # PA5-104093) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-104093
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human RGS20(Accession O76081), corresponding to amino acid residues G143-A193.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2853421
产品详细信息
Antibody detects endogenous levels of total RGS20.
靶标信息
Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi (see GNAI1; MIM 139310) and Gq (see GNAQ; MIM 600998) class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G(z)GAP; Gz-selective GTPase-activating protein; Regulator of G-protein signaling 20; regulator of G-protein signaling 20 variant 2; Regulator of G-protein signaling Z1; regulator of G-protein signalling 20; Regulator of Gz-selective protein signaling 1; RGS20
基因别名: 2900073E09Rik; g(z)GAP; gz-GAP; RGS20; RGSZ1; ZGAP1
UniProt ID: (Human) O76081, (Mouse) Q9QZB1
Entrez Gene ID: (Human) 8601, (Mouse) 58175
regulation of transcription, DNA-templated
cell death
regulation of G-protein coupled receptor protein signaling pathway
dorsal/ventral axis specification
cell differentiation
regulation of catenin import into nucleus
positive regulation of GTPase activity
cellular response to organic cyclic compound
negative regulation of canonical Wnt signaling pathway
Wnt signaling pathway involved in somitogenesis
G-protein coupled receptor signaling pathway
negative regulation of signal transduction
termination of G-protein coupled receptor signaling pathway
