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RNF3 Antibody (PA5-96686) in WB
Western blot analysis of RNF3 in extracts of various cell lines. Samples were incubated with RNF3 Polyclonal antibody (Product # PA5-96686) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 30s.
产品信息
PA5-96686
产品规格
种属反应
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-242 of human PCGF3 (NP_0063062)
偶联物
形式
Liquid
浓度
0.8 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2808488
产品详细信息
Immunogen sequence: MLTRKIKLWD INAHITCRLC SGYLIDATTV TECLHTFCRS CLVKYLEENN TCPTCRIVIH QSHPLQYIGH DRTMQDIVYK LVPGLQEAEM RKQREFYHKL GMEVPGDIKG ETCSAKQHLD SHRNGETKAD DSSNKEAAEE KPEEDNDYHR SDEQVSICLE CNSSKLRGLK RKWIRCSAQA TVLHLKKFIA KKLNLSSFNE LDILCNEEIL GKDHTLKFVV VTRWRFKKAP LLLHYRPKMD LL; Positive Samples: Mouse kidney, Mouse heart; Cellular Location: Nucleus
靶标信息
Phosphorylase kinase is a hexadecameric enzyme that is comprised of four copies of four subunits that are encoded by four separate genes: PHKA, PHKB, PHKG, and PH kDa. This serine/threonine specific kinase converts glycogen phosphorylase b to glycogen phosphorylase a, resulting in the release of glucose-1-phophate from glycogen. PHKB (Phosphorylase b kinase regulatory subunit beta) is a 1093 amino acid subunit of phosphorylase kinase that, along with PHKA, has regulatory functions controlled by phosphorylation. Defects in the gene encoding PHKB are the cause of glycogen storage disease type 9B, which is also known as phosphorylase kinase deficiency of liver and muscle. This disease is characterized by a mild phenotype of hepatomegaly with only slightly elevated transaminase and plasma lipids, no clinical muscle involvement, and generally is correlated with a gradual improvement with increasing age. There are four isoforms of PHKB that are produced as a result of alternative splicing events.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: D6S113E; DADB-17J1.3; DKFZp686D20235; DKFZp686N0336; FLJ31942; FLJ36550; FLJ43813; FSH; FSRG1; KIAA9001; MGC129615; MGC40413; NAT; Polycomb group RING finger protein 3; ring finger protein 3; RING finger protein 3A; RING3
基因别名: 2310035N15Rik; AI662857; D630042K08Rik; DONG1; E430039C14; PcgF3; Rnf3; RNF3A
UniProt ID: (Mouse) Q8BTQ0
Entrez Gene ID: (Mouse) 69587
