Invitrogen

RNF4 Monoclonal Antibody (OTI9F10)

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抗体检测数据 (1)

RNF4 Antibody in Western Blot (WB)

RNF4 Antibody in Western Blot (WB)

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RNF4 Antibody (MA5-27424) in WB

Western blot analysis of RNF4 in HEK293T cells in untransfected (Left lane) and transfected (Right lane) samples using 5 µg per lane. The samples were separated by SDS-PAGE and probed with RNF4 (Product # MA5-27424) monoclonal antibody.

RNF4 Antibody in Western Blot (WB)

Product Image Gallery

RNF4 Antibody in Western Blot (WB) — Western blot analysis of RNF4 in HEK293T cells in untransfected (Left lane) and transfected (Right lane) samples using 5 µg per lane. The samples were separated by SDS-PAGE and probed with RNF4 (Product # MA5-27424) monoclonal antibody.

产品信息

MA5-27424

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

-

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

OTI9F10

抗原

Human recombinant protein fragment corresponding to amino acids 1-190 of RNF4 produced in E.coli

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 1% BSA, 50% glycerol

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2723591

靶标信息

The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: E3 ubiquitin ligase RNF4; E3 ubiquitin-protein ligase RNF4; Protein SNURF; RING finger protein 4; Small nuclear ring finger protein; SNURF

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基因别名: AU018689; Gtrgeo8; RES4-26; RNF4; SLX5; SNURF

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UniProt ID: (Human) P78317, (Rat) O88846, (Mouse) Q9QZS2

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Entrez Gene ID: (Human) 6047, (Rat) 29274, (Mouse) 19822

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DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity ubiquitin-protein transferase activity protein binding transcription factor binding zinc ion binding ligase activity nucleosome binding SUMO polymer binding identical protein binding androgen receptor binding ubiquitin protein ligase activity TBP-class protein binding estrogen receptor binding progesterone receptor binding

transcription, DNA-templated protein ubiquitination androgen receptor signaling pathway negative regulation of protein sumoylation proteasome-mediated ubiquitin-dependent protein catabolic process positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter response to arsenic-containing substance protein autoubiquitination protein K63-linked ubiquitination protein K48-linked ubiquitination protein K11-linked ubiquitination protein K6-linked ubiquitination regulation of spindle assembly regulation of kinetochore assembly negative regulation of cell death cellular response to gamma radiation cellular response to hydroxyurea