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Immunogen sequence: GTTTTTTSVK KEELVPSEED FQGITPGAQG PSSRGREPEA RPKRELRERE GPSLGPP
The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 95 kDa retinoblastoma protein binding protein; 95 kDa retinoblastoma-associated protein; BRE1 E3 ubiquitin ligase homolog B; BRE1-B; DKFZp686K191; E3 ubiquitin-protein ligase BRE1B; MGC13051; Rb-associated protein; RBP95; RING finger protein 40; ring finger protein 40, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase BRE1B
基因别名: BRE1B; KIAA0661; RBP95; RNF40; STARING
UniProt ID: (Human) O75150
Entrez Gene ID: (Human) 9810