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产品信息
PA5-68868
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide directed towards the N terminal region of mouse RNF6
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2691404
产品详细信息
This target displays homology in the following species: Mouse: 100%; Rat: 93%
靶标信息
The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp686P0776; E3 ubiquitin-protein ligase RNF6; RLIM-like protein
基因别名: 1200013I08Rik; 5730419H05Rik; AA537053; Rnf6
UniProt ID: (Mouse) Q9DBU5
Entrez Gene ID: (Mouse) 74132
DNA binding
ubiquitin-protein transferase activity
protein binding
zinc ion binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
androgen receptor binding
ubiquitin protein ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
regulation of transcription, DNA-templated
ubiquitin-dependent protein catabolic process
protein ubiquitination
negative regulation of axon extension
protein K27-linked ubiquitination
positive regulation of transcription, DNA-templated
regulation of androgen receptor signaling pathway
protein K48-linked ubiquitination
protein K6-linked ubiquitination
