Invitrogen

RPGR Polyclonal Antibody

RPGR Antibody in Immunocytochemistry (ICC/IF)

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RPGR Antibody (PA5-95953) in ICC/IF

Immunofluorescence analysis of RPGR in mouse retina cells. Samples were incubated with RPGR Polyclonal antibody (Product # PA5-95953) using a dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.

RPGR Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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产品信息

PA5-95953

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

1:50-1:200

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human RPGR (NP_0010300251)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.44 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.05% ProClin 300

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2807755

产品详细信息

Immunogen sequence: MREPEELMPD SGAVFTFGKS KFAENNPGKF WFKNDVPVHL SCGDEHSAVV TGNNKLYMFG SNNWGQLGLG SKSAISKPTC VKALKPEKVK LAACGRNHTL VSTEGGNVYA TGGNNEGQLG LGDTEERNTF HVISFFTSEH KIKQLSAGSN TSAALTEDGR LFMWGDNSEG QIGLKNVSNV CVPQQVTIGK PVSWISCGYY HSAFVTTDGE LYVFGEPENG KLGLPNQLLG NHRTPQLVSE IPEKVIQVAC GGEHTVVLTE; Positive Samples: Y79, Mouse heart; Cellular Location: Cytoplasm, Golgi apparatus, centrosome, cilium axoneme, cilium basal body, cytoskeleton, flagellum axoneme, microtubule organizing center

靶标信息

This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.

仅用于科研。不用于诊断过程。未经明确授权不得转售。