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RPGRIP1L Antibody (PA5-100049) in ICC/IF
Immunofluorescent analysis of RPGRIP1L in HepG2. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C) incubated with RPGRIP1L polyclonal antibody (Product # PA5-100049) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 at a dilution of 1:600.
产品信息
PA5-100049
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human RPGRIP1L(Accession Q68CZ1), corresponding to amino acid residues E72-L122.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2815579
产品详细信息
Antibody detects endogenous levels of total RPGRIP1L.
靶标信息
The protein encoded by this gene can localize to the basal body-centrosome complex or to primary cilia and centrosomes in ciliated cells. The encoded protein has been found to interact with nephrocystin-4. Defects in this gene are a cause of Joubert syndrome type 7 and Meckel syndrome type 5. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp686C0668; fantom; fantom homolog; Nephrocystin-8; Protein fantom; protein phosphatase 1, regulatory subunit 134; RPGR-interacting protein 1-like protein; RPGRIP1-like; RPGRIP1-like protein
基因别名: 1700047E16Rik; 4931437C01; CORS3; FTM; JBTS7; KIAA1005; MKS5; NPHP8; PPP1R134; RGD1311099; RPGRIP1L
UniProt ID: (Human) Q68CZ1, (Mouse) Q8CG73
Entrez Gene ID: (Human) 23322, (Mouse) 244585, (Rat) 307724
in utero embryonic development
establishment of planar polarity
kidney development
liver development
establishment or maintenance of cell polarity
determination of left/right symmetry
regulation of smoothened signaling pathway
neural tube patterning
cerebellum development
lateral ventricle development
olfactory bulb development
corpus callosum development
embryonic forelimb morphogenesis
embryonic hindlimb morphogenesis
cilium assembly
camera-type eye development
nose development
negative regulation of G-protein coupled receptor protein signaling pathway
pericardium development
cochlea development
brain development
telencephalon development
limb morphogenesis
cilium morphogenesis
head development
biological_process
